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Study shows Plavix allergic reactions can be treated with steroids and antihistamines

Study shows Plavix allergic reactions can be treated with steroids and antihistamines A clinical study of cardiac patients suffering allergic reactions after using the widely-prescribed drug clopidogrel, also known by the pharmaceutical name Plavix, has found that allergic symptoms can be alleviated with a combination of steroids and antihistamines. This kind of a treatment can prove to be an effective option for allowing the patients to remain on the drug, as per doctors from the Thomas Jefferson University Hospital.

From Sciencedaily.com:

Eighty-eight percent (21 of 24) were able to stay on Plavix uninterrupted after being treated with the antihistamines and a short course of steroids. Primary Investigator Michael P. Savage, M.D., director, Cardiac Catheterization Laboratory at Thomas Jefferson University Hospital and Kimberly L. Campbell, M.D., cardiology fellow and lead author, presented their findings at the American College of Cardiology’s Annual Scientific Session on March 30 2009.

“This is a very important study for many cardiac patients but especially those with stents,” said Savage. “Every patient who receives a stent must take Plavix to help prevent stent thrombosis which is clotting of the stent. This obviously poses major problems if the patient suffers an allergic reaction to the medication. To discontinue taking the drug can lead to a heart attack which may be fatal. Those with a drug eluting stent are required to be on the drug for at least one year. Our patients with drug eluting stents actually averaged 17 months on Plavix versus the minimum of one year. That’s a very long time to not be on a medication that may save your life.”

Plavix is considered to be one of the most widely prescribed drugs on a worldwide basis and it is estimated that approximately six percent of Plavix users display some signs of allergic reaction(s). This first-of-its-kind systematic study clearly demonstrates drug allergy can be effectively managed without discontinuing the usage after experiencing the allergic symptoms.

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